P.F. Zabrodskii, Saratov Military Institute of Biological and Chemical Safety, Honored Worker of Science
of the Russian Federation, Faculty of Technology of Destruction of Chemical Weapon and Toxic
Substances; Professor; Doctor of Medical Science; A.A. Svistunov, Saratov State Medical University,
Professor; Doctor of Medical Science; V.G. Lim - Saratov State Medical University, Department of
Narcology; Senior Lecturer, Doctor of Medical Science; V.F.Grichin - Saratov State Medical University;
Senior Lecturer. E-mail: pfzabrodsky@gmail.com
Publishing author - Pavel Frantsevich Zabrodskii
410000, Saratov, PO BOX 10,.
It was established in experiments on noninbred rats, that chronic intoxication of ethanol (30 days, total
dose - 6,0 LD50) significantly reduces concentration in a blood of cytokines IFN?, IL-2, IL-4, IL-10, increase
concentration in a blood of IL-6, reduces an interrelation IFN?/IL-4 in comparison with the control,
suppresses of immune responses, that testifies to the greater lesion of Th1-cells in comparison with Th2-
lymphosytes.
Keywords: ethanol, immunotoxity, cytokines, Тh1, Th2- lymphosytes.
RUSSIAN OPEN MEDICAL JOURNAL; YEAR & VOLUME - ISSUE: 2012. VOLUME 1 - ISSUE 2
The material in Annex
Док. 671079
Опублик.: 14.04.14
Число обращений: 0
Забродский Павел Францевич
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