Моноклональные антитела в диагностике низкодифференцированных глиомНазад
Моноклональные антитела в диагностике низкодифференцированных глиом
Баклаушев В.П., Павлов К.А., Чехонин В.П
Биомедицинская химия 2009, т.55, N 2, с.140-154
The review is focused on the modem methods of radioimmune diagnostics of high-grade gliomas with monoclonal antibodies and other approaches of radioimmunolocalisation with pretargeted bispecific antibodies. High-grade tumor-related proteins were analysed as potential targets for radiolabeled antibodies. Recent experimental and clinical data and the most promising immunochemical approaches for diagnostic and targeted therapy of gliomas with tumor-specific antibodies are discussed.
